D.A. Amanda Jaffe, star of Margolin's Wild Justice, is representing an insane derelict charged with a hideous murder. Her father, Frank, is the attorney for a notorious mobster charged with the murder of a junkie. Both clients claim to be innocent-despite overwhelming forensic evidence. But what if the fingerprints, ballistics tests, and other evidence analyzed by the crime lab are not what they seem? Is it possible that a CSI technician would misuse his position to frame innocent people? When Amanda starts looking too closely at the seemingly air-tight evidence in these two apparently unconnected cases, people start to die and she discovers that a madman with the power to alter the truth is on the loose.